If you’re looking for a juicy burger that’s packed with bold flavor, this Avocado Pepper Jack Bison Burger is a delicious choice. Lean ground bison, creamy avocado, spicy Pepper Jack cheese, and fresh vegetables come together on a soft bakery bun for an unforgettable meal. Whether you’re grilling for family dinner or hosting a backyard cookout, this bison burger recipe is simple, satisfying, and full of fresh flavor.
Why You’ll Love This Recipe
- Juicy, lean bison with rich, hearty flavor.
- Creamy avocado balances the spicy Pepper Jack cheese.
- Ready in about 20 minutes.
- Perfect for weeknight dinners or summer grilling.
- Family-friendly and easy to customize.
- Great alternative to traditional beef burgers.
Ingredients

- 1 Artesano® Bakery Bun
- ¼ pound ground bison
- Salt, to taste
- Black pepper, to taste
- 1 butter lettuce leaf
- 2 tomato slices
- 1 slice Pepper Jack cheese
- ½ avocado, sliced
- 2 tablespoons herbed mayonnaise
Instructions
- Preheat your grill to medium heat.
- Season the ground bison with salt and black pepper.
- Form the meat into a burger patty slightly larger than the bun.
- Grill for approximately 6–7 minutes per side for medium doneness, or cook to your preferred temperature.
- During the last minute of cooking, place the Pepper Jack cheese on the burger so it melts.
- Toast the bun lightly if desired.
- Spread herbed mayonnaise on the top bun.
- Layer the bottom bun with butter lettuce and tomato slices.
- Place the grilled burger on top, followed by the melted cheese and sliced avocado.
- Close the burger with the top bun and serve immediately. This Avocado Pepper Jack Bison Burger pairs wonderfully with fries, sweet potato wedges, or a fresh salad.

Tips & Tricks
- Avoid overworking the ground bison to keep the burger tender.
- Since bison is leaner than beef, avoid overcooking it.
- Toasting the bun adds texture and helps prevent sogginess.
- Add sliced red onion or pickles for extra crunch.
- Substitute chipotle mayo for a smoky kick.
- Use whole wheat buns for a healthier option.
Details
- Prep Time: 10 minutes
- Cook Time: 14 minutes
- Total Time: 24 minutes
- Yield: 1 serving
- Category: Main Course
- Method: Grilling
- Cuisine: American
- Difficulty: Easy
- Dietary Information: High-protein, low in carbohydrates, and naturally gluten-free when served on a gluten-free bun.

Notes
- For a milder burger, replace Pepper Jack with Monterey Jack cheese.
- Add crispy fried onions for extra texture.
- Serve with grilled corn, potato salad, or coleslaw.
- Double or triple the recipe for cookouts and parties.
Nutrition (Approximate)
- Calories: 620
- Protein: 36g
- Carbohydrates: 31g
- Fat: 39g
- Fiber: 7g
- Sugar: 6g
- Sodium: 760mg
FAQ
Is bison healthier than beef?
Yes. Bison is generally leaner than beef while providing plenty of protein, iron, and vitamin B12.
Can I cook this burger in a skillet?
Absolutely. Cook over medium-high heat for about 5–6 minutes per side.
What temperature should a bison burger reach?
Cook to an internal temperature of 160°F (71°C) for ground bison to ensure food safety.
What toppings go well with a bison burger?
Avocado, caramelized onions, mushrooms, bacon alternatives such as turkey bacon, lettuce, tomato, and spicy sauces all pair well.
Can I prepare the patties ahead of time?
Yes. Shape the patties and refrigerate them for up to 24 hours before grilling.
Storage
Refrigerator: Store cooked burger patties in an airtight container for up to 3 days.
Freezer: Freeze cooked or uncooked patties for up to 3 months. Separate with parchment paper before freezing.
Reheating: Warm gently in a skillet over medium heat or microwave in short intervals until heated through.

Similar Recipes

Avocado Pepper Jack Bison Burger Recipe
Ingredients
- 1 Artesano® Bakery Bun
- ¼ pound ground bison
- Salt to taste
- Black pepper to taste
- 1 butter lettuce leaf
- 2 tomato slices
- 1 slice Pepper Jack cheese
- ½ avocado sliced
- 2 tablespoons herbed mayonnaise
Instructions
- Preheat your grill to medium heat.
- Season the ground bison with salt and black pepper.
- Form the meat into a burger patty slightly larger than the bun.
- Grill for approximately 6–7 minutes per side for medium doneness, or cook to your preferred temperature.
- During the last minute of cooking, place the Pepper Jack cheese on the burger so it melts.
- Toast the bun lightly if desired.
- Spread herbed mayonnaise on the top bun.
- Layer the bottom bun with butter lettuce and tomato slices.
- Place the grilled burger on top, followed by the melted cheese and sliced avocado.
- Close the burger with the top bun and serve immediately. This Avocado Pepper Jack Bison Burger pairs wonderfully with fries, sweet potato wedges, or a fresh salad.
Notes
- For a milder burger, replace Pepper Jack with Monterey Jack cheese.
- Add crispy fried onions for extra texture.
- Serve with grilled corn, potato salad, or coleslaw.
- Double or triple the recipe for cookouts and parties.
Conclusion
This Avocado Pepper Jack Bison Burger is everything you want in a gourmet homemade burger—juicy, flavorful, creamy, and incredibly easy to prepare. Whether you’re trying bison for the first time or looking for a new grilling favorite, this recipe is sure to become a regular part of your meal rotation.

