In a medium bowl, combine the shredded rotisserie chicken and Frank's RedHot Sauce.
Toss everything together until the chicken is evenly coated with the buffalo sauce.
Lay the romaine lettuce leaves on a serving platter.
Divide the buffalo chicken mixture evenly among the lettuce leaves.
Top each wrap with halved cherry tomatoes, sliced red onion, and two slices of avocado.
If desired, drizzle each wrap with ranch dressing before serving.
Serve immediately and enjoy these Easy Low Carb Buffalo Chicken Lettuce Wraps while the lettuce is crisp and fresh.